How is PRIS characterized in terms of frequency and mortality?

How is PRIS characterized in terms of frequency and mortality?

• A. Common and low mortality
• B. Rare but potentially fatal
• C. Very common with low mortality
• D. Ubiquitous with 100% mortality

Answer: (B)

Propofol Infusion Syndrome is a rare but life-threatening complication of prolonged, high-dose propofol use. Its infrequency means you don’t see it often, but when it does occur it can be fatal due to severe metabolic derangements like acidosis, rhabdomyolysis, hyperlipidemia, cardiac failure, and arrhythmias. The risk rises with lengthy infusions in critically ill patients, so the most accurate description is that it is rare yet potentially fatal. This is different from being common or ubiquitous, which would imply it happens frequently in practice, or from a situation with universal mortality, which isn’t the case.

Propofol Infusion Syndrome is a rare but life-threatening complication of prolonged, high-dose propofol use. Its infrequency means you don’t see it often, but when it does occur it can be fatal due to severe metabolic derangements like acidosis, rhabdomyolysis, hyperlipidemia, cardiac failure, and arrhythmias. The risk rises with lengthy infusions in critically ill patients, so the most accurate description is that it is rare yet potentially fatal. This is different from being common or ubiquitous, which would imply it happens frequently in practice, or from a situation with universal mortality, which isn’t the case.